Intravascular Large B-Cell Lymphoma of the Skin: Typical Clinical Manifestations and a Favourable Response to Rituximab-Containing Therapy
2009; Karger Publishers; Volume: 219; Issue: 4 Linguagem: Inglês
10.1159/000228328
ISSN1421-9832
AutoresRobert Feldmann, Michael Schierl, Matthias Sittenthaler, Reinhild Jahn, Christian Wogritsch, Lorenzo Cerroni, Andreas Steiner, Friedrich Breier,
Tópico(s)Vascular Tumors and Angiosarcomas
ResumoIntravascular large B-cell lymphoma (IVBCL) is a rare malignant neoplasm characterized by the proliferation of large B cells within the blood vessels. The disease can be limited to the skin, but involvement of other organs is common. We report a case of cutaneous IVBCL in a 62-year-old man with minimal histological changes in contrast to prominent skin lesions. The patient was successfully treated with rituximab in combination with CHOP chemotherapy.
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