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Hydroxyl-Directed Nitrile Oxide Cycloaddition Reactions with Cyclic Allylic Alcohols

2007; American Chemical Society; Volume: 9; Issue: 19 Linguagem: Inglês

10.1021/ol7017032

1523-7060

Nina Becker, Erick M. Carreira,

Synthetic Organic Chemistry Methods

Diastereoselective cycloaddition reactions between a nitrile oxide and cyclic allylic alcohols are reported. The products isolated are densely functionalized building blocks that are not otherwise easily accessed with existing methods and concepts previously established for the construction of acyclic polyketides.