Physical-chemical properties of cross-linked chitosan electrospun fiber mats
2012; Elsevier BV; Volume: 31; Issue: 8 Linguagem: Inglês
10.1016/j.polymertesting.2012.07.010
ISSN1873-2348
AutoresVítor Sencadas, Daniela M. Correia, Clarisse Ribeiro, Susana Moreira, Gabriela Botelho, José Luís Gómez Ribelles, S. Lanceros‐Méndez,
Tópico(s)Advanced Sensor and Energy Harvesting Materials
ResumoChitosan fiber mats were successfully processed by electrospinning. The as-spun fiber mats were neutralized with ethanol and cross-linked with glutaraldehyde. A decrease of the fiber average diameter from 243 ± 43 nm down to 215.53 nm was observed for the neutralized and cross-linking chitosan membrane. It was found that the processing conditions do not alter the initial deacetylation degree of the polymer. Polymer crystallinity index showed a decrease from 61% for the Protasan material down to 17% for the cross-linking fiber mats. A swelling index up to 1000% was observed for the cross-linked samples. Preliminary MC-3T3-E1cell culture results showed good cell adhesion and proliferation in the cross-linked chitosan fiber mats.
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