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Artigo Revisado por pares
BIBTEX RIS

Simple in vitro methods for titrating Feline Immunodeficiency Virus (FIV) and FIV neutralizing antibodies

1992; Elsevier BV; Volume: 37; Issue: 3 Linguagem: Inglês

10.1016/0166-0934(92)90026-a

ISSN

1879-0984

Autores

F Tozzini, Donatella Matteucci, Patrizia Bandecchi, Fulvia Baldinotti, Alessandro Poli, Mauro Pistello, K H Siebelink, Luca Ceccherini‐Nelli, Mauro Bendinelli,

Tópico(s)

HIV Research and Treatment

Resumo

The feline immunodeficiency virus (FIV) readily produced syncytia in Crandell feline kidney (CrFK) cells adapted to a medium containing 0.5% fetal calf serum, a variety of growth factors and other supplements. This finding has been exploited to develop simple and sensitive virus titration and neutralization assays. High titre neutralizing antibodies were detected in cats infected naturally and experimentally with FIV, but not in uninfected animals.

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