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Ncor2 is required for hematopoietic stem cell emergence by inhibiting Fos signaling in zebrafish

2014; Elsevier BV; Volume: 124; Issue: 10 Linguagem: Inglês

10.1182/blood-2013-11-541391

1528-0020

Yonglong Wei, Dongyuan Ma, Ya Gao, Chunxia Zhang, Lu Wang, Feng Liu,

Aquaculture disease management and microbiota

Key Points Ncor2 is essential for HSC emergence in zebrafish. Ncor2 inhibits Fos-Vegfd signaling through recruitment of histone deacetylase 3 (Hdac3).