Portal de Periódicos da CAPES

Antidote Review: Fomepizole for Methanol Poisoning

2003; Lippincott Williams & Wilkins; Volume: 10; Issue: 1 Linguagem: Inglês

10.1097/00045391-200301000-00015

1536-3686

Mark B. Mycyk, Jerrold B. Leikin,

Renal function and acid-base balance

Fomepizole (Antizol) was recently approved by the US Food and Drug Administration for treatment of methanol poisoning. By inhibiting the hepatic enzyme alcohol dehydrogenase, it presents formation of toxic metabolites with far fewer consequences than traditional ethanol therapy. It appears that fomepizole will become standard therapy for methanol intoxication as it is for ethylene glycol poisoning.