Produção Nacional
Revisado por pares
The systems containing clays and clay minerals from modified drug release: A review
2012; Elsevier BV; Volume: 103; Linguagem: Inglês
10.1016/j.colsurfb.2012.10.068
ISSN1873-4367
AutoresLuís Alberto de Sousa Rodrigues, Ana Figueiras, Francisco Veiga, Rivelilson Mendes de Freitas, Lívio César Cunha Nunes, Edson C. Silva-Filho, Cleide Maria da Silva Leite,
Tópico(s)Therapeutic Uses of Natural Elements
ResumoClays are materials commonly used in the pharmaceutical industry, either as ingredients or as active ingredients. It was observed that when they are administered concurrently, they may interact with drugs reducing their absorption. Therefore, such interactions can be used to achieve technological and biopharmaceutical advantages, regarding the control of release. This review summarizes bibliographic (articles) and technological (patents) information on the use of systems containing clays and clay minerals in modified drug delivery. In this area, formulations such natural clay, commercial clay, synthetic clay, composites clay-polymers, nanocomposites clay-polymers, films and hidrogels composites clay-polymers are used to slow/extend or vectorize the release of drugs and consequently they increase their bioavailability. Finally, this review summarizes the fields of technology and biopharmaceutical applications, where clays are applied.
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