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Monosized magnetic particles and their use in selective cell separation

1988; Wiley; Volume: 17; Issue: 1 Linguagem: Inglês

10.1002/masy.19880170113

0258-0322

J. Ugelstad, Arvid Berge, T. Ellingsen, Oddvar Aune, Lars Kilaas, Tom-Nils Nilsen, Ruth Schmid, Per Stenstad, S. Funderud, Gunnar Kvalheim, Kjell Nustad, T. Lea, F Vartdal, Håvard E. Danielsen,

Protein purification and stability

Abstract The principle of activated swelling has made available polymer particles in the range of 1–100 μm, highly uniform in size, and with great variations in morphology and chemical composition. A short description of the method is given. On the basis of monosized porous macroreticular particles, monosized magnetic polymer particles (MMP) are prepared which are uniform in size as well as in content of magnetic oxides. These particles have found applications in a number of selective cell separation procedures. Special types of MMP have been developed for isolation of organelles and viruses. The use of MMP as contrast agent in magnetic resonance imaging is shortly described.