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Detection of microbubbles released by oxygenators during cardiopulmonary bypass by intraoperative transesophageal echocardiography

1990; Elsevier BV; Volume: 66; Issue: 4 Linguagem: Inglês

10.1016/0002-9149(90)90718-g

1879-1913

Luigi Meloni, Pietro A. Abbruzzese, Gabriele Cardu, Giorgio M. Aru, Pietro Loriga, Alessandro Ricchi, Valentino Martelli, A Cherchi,

Airway Management and Intubation Techniques

Despite the improvements in cardiopulmonary bypass techniques, release of microbubbles in the systemic arterial circulation still occurs. It is believed that microemboli, prolonged arterial hypotension, defective cerebral blood flow autoregulation and nonpulsatile flow during cardiopulmonary bypass play a role in determining neurologic damage after cardiopulmonary bypass.1,2 Gaseous and particulate microemboli may originate from the pump-oxygenator system as well as from the cardiac chambers and pulmonary veins.1,3 In this study, transesophageal echocardiography was used to detect microbubbles reaching the arterial circulation during cardiopulmonary bypass. Two different types of oxygenators (bubbles and hollow fibers) were used to assess differences in their production of microbubbles.