Artigo Revisado por pares

The nucleotide sequence of the human β-globin gene

1980; Cell Press; Volume: 21; Issue: 3 Linguagem: Inglês

10.1016/0092-8674(80)90428-6

ISSN

1097-4172

Autores

Richard M. Lawn, Argiris Efstratiadis, Catherine M. O’Connell, Tom Maniatis,

Tópico(s)

Hemoglobinopathies and Related Disorders

Resumo

We report the complete nucleotide sequence of the human β-globin gene. The purpose of this study is to obtain information necessary to study the evolutionary relationships between members of the human β-like globin gene family and to provide the basis for comparing normal β-globin genes with those obtained from the DNA of individuals with genetic defects in hemoglobin expression.

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