Neuronotrophic effects of skeletal muscle fractions on neurite development
1984; Wiley; Volume: 7; Issue: 3 Linguagem: Inglês
10.1002/mus.880070305
ISSN1097-4598
AutoresLinda Hsu, D. Natyzak, Gene L. Trupin,
Tópico(s)Apelin-related biomedical research
ResumoAbstract Soluble fractions of chick embryonic skeletal muscle stimulated radial outgrowth of long neurites from peripheral ganglia. Dorsal root ganglia were more responsive to the growth stimulus of muscle fractions than sympathetic ganglia. Muscle fractions from chicks immobilized with d‐tubocurarine chloride (dtc) were significantly more effective in stimulating growth than normal muscle fractions. Neuritic outgrowth stimulated by muscle fractions was not blocked by antisera to the Nerve Growth Factor (NGF) indicating that these neuronotrophic effects were not due to NGF.
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