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BIBTEX RIS

Chronic disseminated histoplasmosis with lesions restricted to the mouth: case report

2006; UNIVERSIDADE DE SÃO PAULO; Volume: 48; Issue: 2 Linguagem: Inglês

10.1590/s0036-46652006000200012

1678-9946

Antônio Carlos Francesconi do Valle, Luiz Carlos Moreira, Rodrigo Almeida‐Paes, João Soares Moreira, Cláudia Vera Pizzini, Mauro de Medeiros Muniz, Rosely Maria Zancopé‐Oliveira,

Antifungal resistance and susceptibility

We report a rare case of chronic disseminated histoplasmosis with several ulcerated lesions in the oral cavity in an alcoholic patient without human immunodeficiency virus infection, with no detectable signs and symptoms of systemic disease or extraoral manifestations. Histopathological analysis revealed chronic inflammatory process with granulomas containing Histoplasma-like organisms. The isolation of Histoplasma capsulatum provided the definitive diagnosis. Treatment with itraconazole resulted in complete remission of oral lesions. As far we aware, this is the second case report of oral histoplasmosis in an HIV negative patient described in Brazil.