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Ligation of Nanoparticle Coated DNA Cleaved with Restriction Enzymes

2007; American Chemical Society; Volume: 19; Issue: 15 Linguagem: Inglês

10.1021/cm070850e

1520-5002

Joseph M. Kinsella, Margarita V. Shalaev, Albena Ivanisevic,

Molecular Junctions and Nanostructures

In nature, DNA is a dynamic molecule regulated, reproduced, and destroyed using a host of enzymatic reactions. This report describes how templated DNA can be used as a dynamic material scaffold capable of being enzymatically reduced to smaller fragments and subsequently rejoined to become a long strand.