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A new integron carrying VIM-2 metallo-β-lactamase gene cassette in a Serratia marcescens isolate

2002; Elsevier BV; Volume: 42; Issue: 3 Linguagem: Inglês

10.1016/s0732-8893(01)00352-2

1879-0070

Jong Hwa Yum, Dongeun Yong, Kyungwon Lee, Hyun Sook Kim, Yunsop Chong,

Bacterial biofilms and quorum sensing

Serratia marcescens is an important nosocomial pathogen which is often resistant to multiple antimicrobial agents. An imipenem-resistant S. marcescens isolate from a urine specimen was found to carry a blaVIM-2 gene cassette on a class 1 integron. This finding indicates that blaVIM-2 is presently spreading even to Serratia spp. in Korea, which could compromise the usefulness of carbapenem in the treatment of multi-resistant Gram-negative bacilli infections. Clinical laboratory should be able to detect the VIM-2-producing isolates with even low carbapenem MIC.