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Neuropathological Consequences of Chemically and Electrically Induced Seizures

1986; Wiley; Volume: 462; Issue: 1 Linguagem: Inglês

10.1111/j.1749-6632.1986.tb51253.x

1749-6632

Brian S. Meldrum,

Epilepsy research and treatment

Annals of the New York Academy of SciencesVolume 462, Issue 1 p. 186-193 Neuropathological Consequences of Chemically and Electrically Induced Seizures BRIAN S. MELDRUM, BRIAN S. MELDRUM Department of Neurology Institute of Psychiatry De Crespigny Park London SE5 8AF, United KingdomSearch for more papers by this author BRIAN S. MELDRUM, BRIAN S. MELDRUM Department of Neurology Institute of Psychiatry De Crespigny Park London SE5 8AF, United KingdomSearch for more papers by this author First published: March 1986 https://doi.org/10.1111/j.1749-6632.1986.tb51253.xCitations: 28AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat References 1 Meldrum, B. S. & J. A. N. Corsellis. 1984. Epilepsy. In Greenfield's Neuropathology. J. H. Adams, J. A. N. Corsellis & L. W. Duchen, Eds.: 921–950. E. Arnold. London , England . 2 Meldrum, B. 1981. Metabolic effects of prolonged epileptic seizures and the causation of epileptic brain damage. In Metabolic Disorders of the Nervous System. F. C. Rose, Ed.: 175–187. Pitman Medical. London , England . 3 Meldrum, B. S. 1983. Metabolic factors during prolonged seizures and their relation to nerve cell death. Adv. Neurol. 34: 261–275. 4 Corsellis, J. A. N. & A. Meyer. 1954. Histological changes in the brain after uncomplicated ECT. J. Ment. Sci. 100: 375–383. 5 Hartelius, U. 1952. Cerebral changes following electrically induced convulsions. An experimental study on cats. Acta Psychiatr. Neurol. Scand. (Suppl. 77): 1–128. 6 Madow, L. 1956. Brain changes in electro-shock therapy. Am. J. Psychiatry 113: 337–347. 7 Meyer, A. 1963. Epilepsy. In Greenfield's Neuropathology. 2nd edit.: 602–620. Edward Arnold. London , England . 8 Weiner, R. D. 1984. Does electroconvulsive therapy cause brain damage. Behav. Brain Sci. 7: 1–54. 9 Zeman, W. 1950. Zur Frage der Hirngewebeschädigung durch Heilkrampf behandlung. Arch. Psychiatr. Nervepkr. 184: 440–457. 10 Calloway, S. P., R. J. Dolan, R. J. Jacoby & R. Levy. 1981. ECT and cerebral atrophy: a computed tomographic study. Acta Psychiatr. Scand. 64: 442–445. 11 Van Boxel, P., P. K. Bridges, J. R. Bartlett & T. Trader. 1978. Size of cerebral ventricles in 66 psychiatric patients. Br. J. Psychiatry 133: 500–506. 12 Cerletti, Y. & L. Bini. 1940. Le alterazioni istopatologische del sistema nervoso nell'elettroshock. Riv. Sper. Freniatr. Med. Leg. Alienazioni Ment. 64: 2. 13 Siekert, R. G., S. C. Williams & W. F. Windle. 1950. Histologic study of brains of monkeys after experimental electroshock. Arch. Neurol. Psychiatry 63: 79–86. 14 Ferraro, A., L. Roizin & M. Helfand. 1946. Morphologic changes in the brain of monkeys following convulsions electrically induced. J. Neuropathol. Exp. Neurol. 5: 285–308. 15 Masserman, J. H. & M. G. Jacques. 1947. Effects of cerebral electroshock on experimental neuroses in cats. Am. J. Psychiatry 104: 92–99. 16 Colon, E. J. & S. L. H. Notermans. 1975. A long term study of the effects of electroconvulsions on the structure of the cerebral cortex. Acta Neuropathol. 32: 21–25. 17 Dam, M., M. Hertz, T. Bolwig & A. M. Dam. 1981. The number of hippocampal neurons and Purkinje cells in rats after electrically-induced seizures. In Advances in Epileptology XII Epilepsy International Symposium. M. Dam, L. Gram & J. K. Penry, Eds.: 395–401. Raven Press. New York , N.Y. . 18 Dam, A. M. 1982. Hippocampal neuron loss in epilepsy and after experimental seizures. Acta Neurol. Scand. 66: 601–642. 19 Wasterlain, C. G. & F. Plum. 1973. Vulnerability of developing rat brain to electroconvulsive seizures. Arch. Neurol. 29: 38–45. 20 Meldrum, B. S. & R. W. Horton. 1973. Physiology of status epilepticus in primates. Arch. Neurol. 28: 1–9. 21 Dam, A. M. 1980. Epilepsy and neuron loss in the hippocampus. Epilepsia 21: 617–629. 22 Meldrum, B. 1983. Convulsant and anticonvulsant drug mechanism. In Cerebral Blood Flow, Metabolism and Epilepsy. M. Baldy-Moulinier, D. H. Ingvar & B. S. Meldrum, Eds.: 324–335. John Libbey. London , England . 23 Meldrum, B. 1984. Anticonvulsants and the limbic system. In Psychopharmacology of the Limbic System. M. R. Trimble & Z. Zarifian, Eds.: 89–109. Oxford University Press. Oxford , England . 24 Menini, C., B. S. Meldrum, D. Riche, C. Silva-Comte & J. M. Stutzmann. 1980. Sustained limbic seizures induced by intraamygdaloid kainic acid in the baboon: symptomatology and neuropathological consequences. Ann. Neurol. 8: 501–509. 25 Ben-Ari, Y., E. Tremblay, O. P. Ottersen & B. S. Meldrum. 1980. The role of epileptic activity in hippocampal and 'remote' cerebral lesions induced by kainic acid. Brain Res. 191: 79–97. 26 Meldrum, B. S. & J. B. Brierley. 1973. Prolonged epileptic seizures in primates: ischaemic cell change and its relation to ictal physiological events. Arch. Neurol. 28: 10–17. 27 Meldrum, B. S., R. A. Vigoroux & J. B. Brierley. 1973. Systemic factors and epileptic brain damage. Prolonged seizures in paralysed artificially ventilated baboons. Arch. Neurol. 29: 82–87. 28 Meldrum, B. S., R. W. Horton & J. B. Brierley. 1974. Epileptic brain damage in adolescent baboons following seizures induced by allylglycine. Brain 97: 417–428. 29 Turski, W. A., E. A. Cavalheiro, M. Schwarz, S. J. Czuczwar, Z. Kleinrok & L. Turski. 1983. Limbic seizures produced by pilocarpine in rats: behavioural, electroencephalographic and neuropathological study. Behav. Brain Res. 9: 315–335. 30 Aminoff, M. J. & R. O. Simon. 1980. Status epilepticus. Causes, clinical features and consequences in 98 patients. Am. J. Med. 69: 657–666. 31 Sloviter, R. S. 1983. 'Epileptic' brain damage in rats induced by sustained electrical stimulation of the perforant path. I. Acute electrophysiological and light microscopic studies. Brain Res. Bull. 10: 675–697. 32 Popoli, M. & A. Giuditta. 1980. Effect of electroconvulsive shock on polysomes of rabbit brain, liver and kidney. J. Neurochem. 35: 1319–1322. 33 Dunn, A., A. Giuditta & N. Pagliuca. 1971. The effect of electroconvulsive shock on protein synthesis in mouse brian. J. Neurochem. 18: 2093–2099. 34 Giuditta, A., P. Abrescia & B. Tutigliano. 1978. Effect of electroshock on thymidine incorporation into rat brain DNA. J. Neurochem. 31: 983–987. 35 Ferendelli, J. A., A. C. Blank & R. A. Cross. 1980. Relationships between seizure activity and cyclic nucleotide levels in brain. Brain Res. 200: 93–103. 36 Chapman, A. G., B. S. Meldrum & B. K. Siesjö. 1977. Cerebral metabolic changes during prolonged epileptic seizures in rats. J. Neurochem. 28: 1025–1035. 37 Delgado-Escueta, A. V., S. Victor & D. Davidson. 1980. The effects of electroshock convulsions on calcium transport within synaptic terminals. J. Neurochem. 34: 1140–1148. 38 Heinemann, U. & H. D. Lux. 1983. Ionic changes during experimentally induced epilepsies. In Research Progress in Epilepsy. F. C. Rose, Ed.: 87–102. Pitman Medical. London , England . 39 Evans, M., T. Griffiths & B. S. Meldrum. 1983. Early changes in the rat hippocampus following seizures induced by bicuculline or L-allylglycine: a light and electron microscope study. Neuropathol. Appl. Neurobiol. 9: 39–52. 40 Griffiths, T., M. C. Evans & B. S. Meldrum. 1982. Intracellular sites of early calcium accumulation in the rat hippocampus during status epilepticus. Neurosci. Lett. 30: 329–334. 41 Griffiths, T., M. C. Evans & B. S. Meldrum. 1984. Status epilepticus: the reversibility of calcium loading and acute neuronal pathological changes in the rat hippocampus. Neuroscience 12: 557–567. 42 Bazan, N. G. 1971. Changes in free fatty acids of brain by drug-induced convulsions, electroshock and anaesthesia. J. Neurochem. 18: 1379–1385. 43 Chapman, A. G. 1981. Free fatty acid release and metabolism of adenosine and cyclic nucleotides during prolonged seizures. In Neurotransmitters, Seizures and Epilepsy. P. L. Morselli, K. G. Lloyd, W. Löscher, B. Meldrum & E. Reynolds, Eds.: 165–173. Raven Press. New York , N.Y. . 44 Schlaepfer, W. W. & L. A. Freeman. 1980. Calcium-dependent degradation of mammalian neurofilaments by soluble tissue factor(s) from rat spinal cord. Neuroscience 5: 2305–2314. 45 Meldrum, B. S. 1984. Calcium entry blockers and cerebral function: introduction In Calcium Entry Blockers in Cardiovascular and Cerebral Dysfunctions. T. Godfraind, A. Hermann & D. Wellens, Eds.: 207–219. Martinus Nijhoff Publishers. The Hague , Holland . 46 Borgers, M., F. Thone, & J. M. Neuten. 1981. The subcellular distribution of calcium and the effects of calcium-antagonists as evaluated with a combined oxalate-pyroantimonate technique. Acta Histochem. Suppl. 24: 327–332. 47 Griffiths, T., M. C. Evans & B. S. Meldrum. 1983. Intracellular calcium accumulation in rat hippocampus during seizures induced by bicuculline or L–allylglycine. Neuroscience 10: 385–395. 48 Evans, M. C., T. Griffiths & B. S. Meldrum. 1984. Kainic acid seizures and the reversibility of calcium loading in vulnerable neurons in the hippocampus. Neuropathol. Appl. Neurobiol. 10: 285–302. 49 Sackeim, H. A., I. Prohovnick, P. Decina, S. Malitz & S. Resor. 1983. Anticonvulsant properties of electroconvulsive therapy: theory and case report. In Cerebral Blood Flow, Metabolism and Epilepsy. M. Baldy-Moulinier, D. H. Ingvar & B. S. Meldrum, Eds.: 370–377. John Libbey. London , England . Citing Literature Volume462, Issue1Electroconwlsive Therapy: Clinical and Basic Research IssuesMarch 1986Pages 186-193 ReferencesRelatedInformation