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Capsule enteroscopy vs. other diagnostic procedures in diagnosing obscure gastrointestinal bleeding: a cost???effectiveness study

2007; Lippincott Williams & Wilkins; Volume: 19; Issue: 7 Linguagem: Inglês

10.1097/meg.0b013e32812144dd

1473-5687

Riccardo Marmo, G. Rotondano, Emanuele Rondonotti, Roberto de Franchis, Roberto D Inc, Maria Grazia Vettorato, Guido Costamagna, Maria Elena Riccioni, Cristiano Spada, Rosario D Angella, Giuseppe Milazzo, Antonio Faraone, Mario Rizzetto, Valeria Barbon, Pietro Occhipinti, Silvia Saettone, Gaetano Iaquinto, Francesco Paolo Rossini,

Helicobacter pylori-related gastroenterology studies

Background Capsule enteroscopy is considered the gold standard for evaluating patients with obscure gastrointestinal bleeding. The costs of capsule enteroscopy examination, however, make it uncertain whether the clinically relevant diagnostic gain is also associated with cost savings. Aim To evaluate the incremental cost–effectiveness ratio of capsule enteroscopy in patients with obscure gastrointestinal bleeding. Methods Retrospective study was carried out in nine Italian gastroenterology units from 2003 to 2005. Data on 369 consecutive patients with obscure gastrointestinal bleeding were collected. The diagnostic yield of capsule enteroscopy vs. other imaging procedures was evaluated as a measure of efficacy. The values of Diagnosis Related Group 175 (€1884.00 for obscure-occult bleeding and €2141.00 for obscure-overt bleeding) were calculated as measures of economic outcomes in the cost analysis. Results Obscure and occult gastrointestinal bleeding was recorded in 177 patients (48%) with a mean duration of anemia history of 17.6±20.7 months. Among patients, 60.9% had had at least one hospital admission, 21.2% at least two, and 1.2% of obscure bleeders up to nine admissions. Overall, 58.4% of patients had positive findings with capsule enteroscopy compared with 28.0% with other imaging procedures (P<0.001). The mean cost of a positive diagnosis with capsule enteroscopy was €2090.76 and that of other procedures was €3828.83 with a mean cost saving of €1738.07 (P<0.001) for one positive diagnosis. Conclusions Capsule enteroscopy is a cost-saving approach in the evaluation of patients with obscure gastrointestinal bleeding.