Portal de Periódicos da CAPES

Modulation of Neurotransmission by Cannabinoids in the Basal Ganglia

1997; Wiley; Volume: 9; Issue: 2 Linguagem: Inglês

10.1111/j.1460-9568.1997.tb01390.x

1460-9568

Michelle Glass, Jonathan M. Brotchie, Yannick P. Maneuf,

Neurotransmitter Receptor Influence on Behavior

European Journal of NeuroscienceVolume 9, Issue 2 p. 199-203 Modulation of Neurotransmission by Cannabinoids in the Basal Ganglia M. Glass, M. Glass Laboratory of Cell Biology, National Institute of Mental Health, 36 Convent Drive, Bethesda, MD 20892 USASearch for more papers by this authorJ. M. Brotchie, J. M. Brotchie Division of Neuroscience, School of Biological Sciences, University of Manchester, Manchester M13 9PT, UKSearch for more papers by this authorY. P. Maneuf, Corresponding Author Y. P. Maneuf Division of Neuroscience, School of Biological Sciences, University of Manchester, Manchester M13 9PT, UKY. P. Maneuf, as aboveSearch for more papers by this author M. Glass, M. Glass Laboratory of Cell Biology, National Institute of Mental Health, 36 Convent Drive, Bethesda, MD 20892 USASearch for more papers by this authorJ. M. Brotchie, J. M. Brotchie Division of Neuroscience, School of Biological Sciences, University of Manchester, Manchester M13 9PT, UKSearch for more papers by this authorY. P. Maneuf, Corresponding Author Y. P. Maneuf Division of Neuroscience, School of Biological Sciences, University of Manchester, Manchester M13 9PT, UKY. P. Maneuf, as aboveSearch for more papers by this author First published: 07 April 2006 https://doi.org/10.1111/j.1460-9568.1997.tb01390.xCitations: 56Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat Reference Albin, R. L., Young, A. B. and Penney, J. B. (1989) The functional anatomy of basal ganglia disorders. Trends Neurosci., 12, 366–375. Anderson, J. J., Kask, A. M. and Chase, T. N. (1996) Effects of cannabinoid receptor stimulation and blockade on catalepsy produced by dopamine receptor antagonists. Eur. J. Pharmacol., 295, 163–168. Anderson, L. A., Anderson, J. J., Chase, T. N. and Waiters, J. R. (1995) The cannabinoid agonists WIN 55, 212–2 and CP 55, 940 attenuate rotational behaviour induced by a dopamine D1 but not a D2 agonist in rats with unilateral lesions of the nigrostriatal pathway. Brain Res., 691, 106–114. Banerjee, S. P., Snyder, S. H. and Mechoulam, R. (1975) Cannabinoids: influence on neurotransmitter uptake in rat brain synaptosomes. J. Pharmacol. Exp. Ther., 194, 74–81. Beckstead, R. M. and Kearsey, K. S. (1985) Immunohistochemical demonstration of differential substance P-, met-enkephalin- and glutamic acid decarboxylase-containing cell body and axon distributions in the corpus striatum of the cat. J. Comp. Neurol., 232, 481–498. Beckstead, R. M. and Cruz, C. J. (1986) Striatal axons to the globus pallidus, entopeduncular nucleus and substantia nigra and substantia nigra come mainly from separate cell populations in cat. Neuroscience, 19, 147–158. Bidaut-Russel, M. and Howlett, A. C. (1991) Cannabinoid receptor-regulated cAMP accumulation in the rat striatum. J. Neurochem., 57, 1769–1773. Clifford, D. B. (1983) Tetrahydrocannabinol for tremor in multiple sclerosis. Ann. Neurol., 13, 669–671. Crawley, J. N., Corwin, R. L., Robinson, J. K., Felder, C. C., Devane, W. A. and Axelrod, J. (1993) Anandamide, an endogenous ligand of the cannabinoid receptor, induces hypomotility and hypothermia in vivo in rodents. Pharmacol. Biochem. Behav., 46, 967–972. Desarnaud, F., Cadas, H. and Piomelli, D. (1995) Anandamide amidohydrolase activity in rat brain microsomes. Identification and partial purification. J. Biol. Chem., 270, 6030–6035. Devane, W. A., Dysarz, F. A., Johnson, M. R., Melvin, L. S. and Howlett, A. C. (1988) Determination and characterization of a cannabinoid receptor in rat brain. Mol. Phamacol., 34, 605–613. Devane, W. A., Hanus, L., Breuer, A., Pertwee, R. G., Stevenson, L. A., Griffin, G., Gibson, D., Mandelbaum, A., Etinger, A. and Mechoulam, R. (1992) Isolation and characterization of a brain constituent that binds to the cannabinoid receptor. Science. 258, 1946–1949. Di Marzo, V., Fontana, A., Cadas, H., Schinelli, S., Cimino, G., Schwartz, J. C. and Piomelli, D. (1994) Formation and inactivation of endogenous cannabinoid anandamide in central neurones. Nature, 372, 686–691. Feigenbaum, J. J., Bergman, F., Richmond, S., Mechoulam, R., Nadler, V., Kloog, Y. and Sokolovsky, M. (1989) Non-psychoptropic cannabinoid act as a functional NMDA receptor blocker. Proc. Natl Acad. Sci. USA, 86, 9584–9587. Felder, C. C., Briley, E. M., Axelrod, J., Simpson, J. T., Mackie, K. and Devane, W. A. (1993) Anandamide. an endogenous cannabimimetic eicosanoid, binds to the cloned human cannabinoid receptor and stimulates receptor-mediated signal transduction. Proc. Natl Acad. Sci. USA, 90, 7656–7660. Felder, C. C., Nielsen, A., Briley, E. M., Palkovits, M., Richardson, J. M., Riggin, R. M. and Becker, G. W. (1996) The role of anandamide and dated fatty acid ethanolamides as endogenous ligands for the CB1 and CB2 cannabinoid receptors. In J. Y. Vanderhoek, (ed.), Frontiers in Bioactive Lipids. 16th International Spring Symposium, Washington DC, USA. Plenum Press, New York, NY . Fride, E., Barg, J., Levy, R., Saya, D., Heldman, E. and Mechoulam, R. (1995) Low doses of anandamides inhibit pharmacological effects of delta-9 tetrahydrocannabinol. J. Pharmacol. Exp. Ther., 272, 699. Gaoni, Y. and Mechoulam, R. (1964) Isolation, structure and partial synthesis of an active constituent of hashish. J. Am. Chem. Soc., 86, 1646–1647. Gimenez-Amaya, J. M. and Graybiel, A. M. (1990) Compartmental origins of the striatopallidal projection in the primate. Neuroscience, 34, 111–126. Glass, M. (1995) Receptor alterations in human neuro-degenerative diseases. PhD Thesis. University of Auckland, New Zealand . Glass, M. and Felder, C. C. (1996) Concurrent stimulation of cannabinoid CBI and dopamine D2 receptors results in an augmentation of forskolin-stimulated cAMP in striatal neurones. Soc. Neurosci. Abstr., 615.4. Glass, M., Faull, R. L. M. and Dragunow, M. (1993) Loss of cannabinoid receptors in the substantia nigra in Huntington's disease. Neuroscience, 56, 523–527. Glass, M., Faull, R. L. M. and Dragunow, M. (1997) Cannabinoid receptors in the human brain: a detailed anatomical and quantitative autoradiographic study in the fetal, neonatal and adult human brain. Neuroscience, in press. Graybiel, A. M. (1990) Neurotransmitters and neuromodulators in the basal ganglia. Trends Neurosci., 13, 244–251. Gueudet, C., Santucci, V., Rinaldi-Carmona, M., Soubrie, P. and Le Fur, G. (1995) The CB1 cannabinoid receptor antagonist SR141716A affects A9 dopamine neuronal activity in the rat. NeuroReport, 6, 1421–1425. Herkenham, M., Lynn, A. B., Little, M. D., Johnson, M. R., Melvin, L. S., De Costa, B. R. and Rice, K. C. (1990) Cannabinoid receptor localization in brain. Proc. Natl Acad. Sci. USA, 87, 1932–1936. Herkenham, M., Lynn, A. B., Johnson, M. R., Melvin, L. S., De Costa, B. R. and Rice, K. C. (1991a) Characterization and localization of the cannabinoid receptors in rat brain—a quantitative in vitro autoradiographic study. J. Neurosci., 11, 563–583. Herkenham, M., Lynn, A. B., De Costa, B. R. and Richfield, E. K. (1991b) Neuronal localization of cannabinoid receptors in the basal ganglia of the rat brain. Brain Res., 547, 267–274. Hershkowitz, M., Goldman, R. and Raz, A. (1977) Effect of cannabinoids on neurotransmitter uptake, ATPase activity and morphology of mouse brain synaptosomes. Biochem Pharmacol., 26, 1327–1331. Hollister, L. E. (1986) Heath aspects of cannabis. Pharmacol. Rev., 38, 1–20. Howes, J. and Osgood, P. (1974) The effect of delta-9 tetrahydrocannabinol on the uptake and release of 14C-dopamine from crude striatal synaptosomal preparation. Neuropharmacology, 13, 1109–1114. Hubner, C. B. and Koob, G. F. (1990) The ventral pallidum plays a role in mediating cocaine and heroin self-administration in the rat. Brain Res., 508, 20–29. Kelley, A. E., Domesick, V. B. and Nauta, W. J. (1982) The amygdalostriatal projection in the rat: an anatomical study by anterograde tracing methods. Neuroscience, 7, 615–630. Mackie, K. and Hille, B. (1992) Cannabinoids inhibit N-type calcium current in neuroblastoma-glioma cells. Proc. Natl Acad. Sci. USA, 89, 3825–3829. Mackie, K., Devane, W. A. and Hille, B. (1993) Anandamide, an endogenous cannabinoid, inhibits N-type calcium currents in N18 cells as a partial agonist. Mol. Pharmacol., 44, 498–503. Mackie, K., Lai, Y., Westenbroek, R. and Mitchell, R. (1995) Cannabinoids activate an inwardly rectifying potassium conductance and inhibit Q-type calcium currents in AtT20 cells transfected with rat brain cannabinoid receptor. J. Neurosci., 15, 6552–6561. Mailleux, P. and Vanderhaeghen, J. J. (1992) Distribution of neuronal cannabinoid receptor in the adult rat brain: a comparative receptor binding radioautography and in situ hybridization histochemistry. Neuroscience, 48, 655–668. Mailleux, P., Parmentier, M. and Vanderhaeghen, J. J. (1992) Distribution of cannabinoid receptor messenger RNA in the human brain: an in situ hybridization histochemistry with oligonucleotides. Neurosci. Lett., 143, 200–204. Maneuf, Y. P., Crossman, A. R. and Brotchie, J. M. (1996a) Modulation of GABAergic transmission in the globus pallidus by the synthetic cannabinoid WIN 55, 212–2. Synapse, 22, 382–385. Maneuf, Y. P., Nash, J. E., Crossman, A. R. and Brotchie, J. M. (1996b) Activation of the cannabinoid receptor by delta-9-tetrahydrocannabinol reduces GABA uptake in the globus pallidus. Eur: J. Pharmacol., 308, 161–164. Martyn, C. N., Illis, L. S. and Thom, J. (1995) Nabilone in the treatment of multiple sclerosis. Lancet, 345, 579. Matsuda, L. A., Lolait, S. J., Brownstein, M. J., Young, A. C. and Bonner, T. I. (1990) Structure of a cannabinoid receptor and functional expression of the cloned cDNA. Nature, 346, 561–564. Matsuda, L. A., Bonner, T. I. and Lolait, S. J. (1993) Localization of cannabinoid receptor mRNA in rat brain. J. Comp. Neurol., 327, 535–550. Miller, A. S. and Walker, J. M. (1995) Effects of a cannabinoid on spontaneous and evoked neuronal activity in the substantia nigra pars reticulata. Eur. J. Pharmacol., 279, 179–185. Munro, S., Thomas, K. L. and Abu-Shaar, M. (1993) Molecular characterization of a peripheral receptor for cannabinoids. Nature, 365, 61–65. Nadler, V., Mechoulam, R. and Sokolovsky, M. (1993) The non-psychotropic cannabinoid (+)-(3S, 4S)-7-hydroxy-delta-6-tetrahydrocannahino1–1, 1-dimethylheptyl (HU 211) attenuates NMDA receptor-mediated neurotoxicity in primary cultures of rat forebrain. Neurosci. Lett., 162, 43–45. Pan, H. S., Penney, J. B. and Young, A. B. (1985) γ-Aminobutyric acid and benzodiazepine receptor changes induced by unilateral 6-hydroxydopamine lesions of the medial forebrain bundle. J. Neurochem., 45, 1396–1404. Pertwee, R. G. (1988) The central neuropharmacology of cannabinoids. Pharmacol. Ther., 36, 189–261. Pertwee, R. G. and Greentree, S. G. (1988) Delta-9-tetrahydrocannabinolinduced catalepsy in mice is enhanced by pretreatment with flurazepain or chlorazepoxide. Neuropharmacology, 27, 485–491. Pertwee, R. G. and Wickens, A. P. (1991) Enhancement by chlordiazepoxide of catalepsy induced in rats by intravenous or intrapallidal injections of enantiomeric cannabinoids. Neuropharmacology, 30, 237–244. Pertwee, R. G., Greentree, S. G. and Swift, P. A. (1988) Drugs which stimulate or facilitate central GABAergic transmission interact synergistically with delta-9-tetrahydrocannabinol to produce marked catalepsy in mice. Neuropharmacology, 27, 1265–1270. Petro, D. J. and Ellenberger, C., Jr (1981) Treatment of human spasticity with delta 9-tetrahydrocannabinol. J. Clin. Pharmacol., 21, Suppl. 8–9, pp. 413S–416S. Poddar, M. K. and Dewey, W. L. (1980) Effect of cannabinoids on catecholamine uptake and release in hypothalamic and striatal synaptosomes. J. Pharmacol. Exp. Ther., 214, 63–67. Richfield, E. K. and Herkenham, M. (1994) Selective vulnerability in Huntington's disease: preferential loss of cannabinoid receptors in lateral globus pallidus. Ann. Neurol., 36, 577–584. Rinaldi-Carmona, M., Barth, F., Heaulme, M., Shire, D., Calandra, B., Congy, C., Martinez, S., Marnani, J., Neliat, G., Caput, D., Ferrera, P., Soubrie, P., Breliere, J.-C. and Le Fur, G. (1994) SR141716A, a potent and selective antagonist of the brain cannabinoid receptor. FEBS Lett., 350, 240–244. Rinaldi-Carmona, M., Pialot, F., Congy, C., Redon, E., Barth, E. Bachy, A., Breliere, J. C., Soubrie, P. and Le Fur, G. (1996) Characterization and distribution of binding sites for [3H]SR141716A, a selective brain (CB1) receptor antagonist, in rodent brain. Life Sci., 58, 1239–1247. Romero, J., Garcia-Palomero, E., Lin, S. Y., Ramos, J. A., Makriyannis, A. and Fernandez-Ruiz, J. J. (1996) Extrapyramidal effects of methanandamide, an analogue of anandamide, the endogenous CB1 receptor ligand. Life Sci., 58, 1249–1257. Sañudo-Peña, M. C., Patrick, S. L., Patrick, R. L. and Walker, J. M. (1996) Effects of intranigral cannabinoids on rotational behaviour in rats: interactions with the dopaminergic system. Neurosci. Lett., 206, 21–24. Scheel-Kruger, J. (1986) Dopamine-GABA interactions: evidence that GABA transmits, modulates and mediates dopaminergic functions in the basal ganglia and limbic system. Acta Neurol. Scand., 73, 849. Scheel-Kruger, J., Magelund, G. and Olianas, M. C. (1981) Role of GABA in the striatal output system: globus pallidus, nucleus entopeduncularis, substantia nigra and nucleus subthalamicus. In G. Di Chiara and G. L. Gessa, (eds), GABA and the Basal Ganglia. Raven Press, New York, pp. 165–185. Shen, M., Piser, T. M., Seybold, V. S. and Thayer, S. A. (1996) Cannabinoid receptor agonists inhibit glutamatergic synaptic transmission in rat hippocampal cultures. J. Neurosci., 16, 4322–4334. Shire, D., Carillon, C., Kaghad, M., Calandra, B., Rinaldi-Carmona, M., Le Fur, G., Caput, D. and Ferrara, P. (1995) An amino-terminal variant of the central cannabinoid receptor resulting from alternative splicing. J. Biol. Chem., 270, 3726–3731. Souilhac, J., Poncelet, M., Rinaldi-Carmona, M., Le Fur, G. and Soubrie, P. (1995) Intrastriatal injection of cannabinoid receptor agonists induced turning behaviour in mice. Pharmacol. Biochem. Behav., 51, 3–7. Sugiura, T., Sachiko, K., Sukagawa, A., Tonegawa, T., Nakane, T., Yamashita, A. and Waku, K. (1996) Enzymatic synthesis of anandamide, an endogenous cannabinoid receptor ligand, through N-acetylphosphatidylethanolamine pathway in testis: involvement of Ca++-dependent transacylase and phosphodiesterase activities. Biochem. Biophys. Res. Commun., 218, 113–117. Tian, Y., Kapatos, G., Granneman, J. G. and Bannon, M. J. (1994) Dopamine and GABA transporters: differential regulation by agents that promote phospholylation. Neurosci. Left., 173, 143–146. Ungerstedt, U. (1968) 6-hydroxydopamine induced degeneration of central monoamine neurones. Eur. J. Pharmacol., 5, 107–110. Venance, L., Piomelli, D., Glowinski, J. and Giaume, C. (1995) Inhibition by anandamide of gap junctions and intercellular calcium signalling in striatal astrocytes. Nature, 376, 590–594. Westlake, T. M., Howlett, A. C., Bonner, T. I., Matsuda, L. A. and Herkenham, M. (1994) Cannabinoid receptor binding and messenger RNA expression in human brain: an in vitro receptor autoradiography and in situ hybridization histochemistry study of normal aged and Alzheimer's brains. Neuroscience, 63, 637–652. Citing Literature Volume9, Issue2February 1997Pages 199-203 ReferencesRelatedInformation