Portal de Periódicos da CAPES

Enantioselective Synthesis of Amaryllidaceae Alkaloids (+)‐Vittatine, (+)‐ epi ‐Vittatine, and (+)‐Buphanisine

2013; Wiley; Volume: 8; Issue: 9 Linguagem: Inglês

10.1002/asia.201300595

1861-4728

Meng‐Xue Wei, Chengtao Wang, Ji‐Yuan Du, Hu Qu, Pei‐Rong Yin, Xu Bao, Xiaoyan Ma, Xian‐He Zhao, Guo‐Biao Zhang, Chun‐An Fan,

Advanced Synthetic Organic Chemistry

Cat. on a hot tin roof: Enantioselective catalytic Michael addition of α-cyanoketones to acrylates under bifunctional organocatalysis was used to construct the unique arylic all-carbon quaternary stereocenter, which is synthetically crucial in the chemical synthesis of optically pure cis-aryl hydroindole alkaloids. The protocol offers an asymmetric route to (+)-vittatine, (+)-epi-vittatine, and (+)-buphanisine. As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.