Elimination of interference due to urea in the determination of meprobamate with p-dimethylaminobenzaldehyde
1963; Elsevier BV; Volume: 8; Issue: 1 Linguagem: Inglês
10.1016/0009-8981(63)90191-8
ISSN1873-3492
Autores Tópico(s)Analytical Methods in Pharmaceuticals
ResumoUrea interferes with the colorimetric method for the determination of serum meprobamate with p-dimethylaminobenzaldehyde. By incubating 1.0 ml of serum at 50° for 15 min with one drop of urease prior to extraction of the drug, this interference can be eliminated, urease does not affect the drug, as it is being extracted, either from water or serum.
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