Testosterone, sex hormone-binding globulin, calculated free testosterone, and oestradiol in male vegans and omnivores
1990; Cambridge University Press; Volume: 64; Issue: 1 Linguagem: Inglês
10.1079/bjn19900014
ISSN1475-2662
AutoresTimothy J. Key, Liane S. Roe, Margaret Thorogood, John W. Moore, Graham Clark, Dennis Y. Wang,
Tópico(s)Hormonal and reproductive studies
ResumoTotal testosterone (T), total oestradiol (E2) and sex hormone-binding globulin (SHBG) concentrations were measured in plasma samples from fifty-one male vegans and fifty-seven omnivores of similar age. Free T concentration was estimated by calculation, in comparison with the omnivores, the vegans had 7% higher total T ( P = 0.250), 23% higher SHBG ( P = 0.001), 3% lower free T ( P = 0.580), and 11% higher E2 ( P = 0.194). In a subset of eighteen vegans and twenty-two omnivores for whom 4 d diet records were available, there were statistically significant correlations between T and polyunsaturated fatty acids ( r 0.37), SHBG and fat ( r 0.43 for total fat, 0.46 for saturated fatty acids and 0.33 for polyunsaturated fatty acids), and SHBG and alcohol ( r –0.39). It is concluded that a vegan diet causes a substantial increase in SHBG but has little effect on total or free T or on E2.
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