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BIBTEX RIS

Preparation of protein-loaded-PLGA microspheres by an emulsion/solvent evaporation process employing LTCC micromixers

2008; Elsevier BV; Volume: 190; Issue: 1-2 Linguagem: Inglês

10.1016/j.powtec.2008.04.093

1873-328X

Roseane Maria Ribeiro-Costa, Márcio Rodrigues da Cunha, Mário Ricardo Góngora-Rubio, P. Michaluart-Júnior, Maria Inês Ré,

Gas Sensing Nanomaterials and Sensors

This study presents the possibilities offered by microfluidic structures for the production of polymeric microspheres, using a process based upon the production of an emulsion. LTCC (Low Temperature Co-fired Ceramics) micromixers have been used for the preparation of polymeric microspheres. The effect of the geometry of the micromixers has been studied, with a specific focus on the size of the microspheres, as well as the control release properties of a model protein loaded within these microspheres.