Artigo Acesso aberto Produção Nacional Revisado por pares

Multiple sclerosis in South America: month of birth in different latitudes does not seem to interfere with the prevalence or progression of the disease

2013; Thieme Medical Publishers (Germany); Volume: 71; Issue: 9A Linguagem: Inglês

10.1590/0004-282x20130098

ISSN

1678-4227

Autores

Yára Dadalti Fragoso, Tarso Adoni, Sandra Maria Garcia de Almeida, Soniza Vieira Alves‐Leon, Walter Oleschko Arruda, Fiorella Barbagelata-Aguero, Joseph Bruno Bidin Brooks, Adriana Carrá, Rinaldo Claudino, Elizabeth Regina Comini-Frota, Éber Castro Corrêa, Alfredo Damasceno, Benito Pereira Damasceno, Ethel Ciampi Díaz, David George Elliff, Ana Patrícia Peres Fiore, Clélia Maria Ribeiro Franco, Maria Cristina B. Giacomo, Sidney Gomes, Marcus Vinícius Magno Gonçalves, Anderson Kuntz Grzesiuk, José Luiz Inojosa, Damacio Ramón Kaimen-Maciel, Kátia Lin, Josiane Lopes, Gisele Alexandre Lourenço, Alejandra Martínez, Mario O. Melcon, Nívea de Macedo Oliveira Morales, Rogério Rizo Morales, Marcos Aurélio Moreira, Shirlene Vianna Moreira, Celso Luis da Silva Oliveira, Francisco Tomaz Menezes de Oliveira, João Batista Miranda Ribeiro, Steve Biko Menezes Hora Alves Ribeiro, Claudia Rodríguez, Liliana Russo, Juliana Safanelli, Kirsty Shearer, Fábio Siquineli, Darwin Vizcarra,

Tópico(s)

Reproductive System and Pregnancy

Resumo

To assess whether the month of birth in different latitudes of South America might influence the presence or severity of multiple sclerosis (MS) later in life.Neurologists in four South American countries working at MS units collected data on their patients' month of birth, gender, age, and disease progression.Analysis of data from 1207 MS patients and 1207 control subjects did not show any significant variation in the month of birth regarding the prevalence of MS in four latitude bands (0-10; 11-20; 21-30; and 31-40 degrees). There was no relationship between the month of birth and the severity of disease in each latitude band.The results from this study show that MS patients born to mothers who were pregnant at different Southern latitudes do not follow the seasonal pattern observed at high Northern latitudes.

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