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Identification of bla OXA-51-like , bla OXA-58 , bla DIM-1 , and bla VIM Carbapenemase Genes in Hospital Enterobacteriaceae Isolates from Sierra Leone

2013; American Society for Microbiology; Volume: 51; Issue: 7 Linguagem: Inglês

10.1128/jcm.00832-13

1098-660X

Tomasz A. Łęski, Umaru Bangura, David Henry Jimmy, Rashid Ansumana, Stephen E. Lizewski, Robert W. Li, David A. Stenger, Chris R. Taitt, Gary J. Vora,

Enterobacteriaceae and Cronobacter Research

We describe the results of a molecular epidemiological survey of 15 carbapenemase-encoding genes from a recent collection of clinical isolates from Mercy Hospital in Bo, Sierra Leone. The most salient findings revealed that (i) 60% of the isolates harbored multiple carbapenemase genes; (ii) the blaDIM-1 gene, which has previously only been reported in The Netherlands, is also circulating in this environment; and (iii) blaOXA-51-like and blaOXA-58 genes, which were thought to reside exclusively in Acinetobacter species, can also be found in members of the Enterobacteriaceae.