Amino acid sequences of mammalian Kazal-type proteinase inhibitors from salivary glands
1993; Elsevier BV; Volume: 106; Issue: 1 Linguagem: Inglês
10.1016/0305-0491(93)90014-v
ISSN0305-0491
AutoresKarl HOCHSTRASSER, Elmar Wächter, Peter W. M. Reisinger, Michael Greim, G.J. Albrecht, Wolfgang Gebhard,
Tópico(s)Coagulation, Bradykinin, Polyphosphates, and Angioedema
Resumo1. The amino acid sequences of bikazins (the double-headed Kazal-type proteinase inhibitors from submandibular glands) isolated from the snow leopard (Unica unica), the European mink (Mustela lutreola), and the European pine marten (Martes martes) were determined. 2. N-terminal domains of bikazins are characterized by a cysteine residue spacing that differs from that of C-terminal domains of bikazins and other Kazal-type proteinase inhibitor domains. 3. N-terminal sequences of bikazins seem to be specific for, and highly conserved within, each Carnivora family.
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