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Intraocular pressure in schizophrenic patients treated with psychiatric medications

2008; Conselho Brasileiro de Oftalmologia; Volume: 71; Issue: 5 Linguagem: Inglês

10.1590/s0004-27492008000500009

1678-2925

Valéria Barreto Novais e Souza, Francisco José Rodrigues de Moura Filho, Fábio Gomes de Matos e Souza, Sergio Augusto Carvalho Pereira Filho, Suele Serra Coelho, Fernando Antônio Mendes Lopes Furtado, Tiago Bessa Almeida Gonçalves, Karla Feitosa Ximenes Vasconcelos,

Sympathectomy and Hyperhidrosis Treatments

In order to assess the occurrence of adverse ocular effects of antipsychotic drugs, we sought to evaluate intraocular pressure of schizophrenic patients treated with psychiatric medications.Twenty-eight outpatients with DSM-IV diagnosis of schizophrenia who met both the inclusion and exclusion criteria were submitted to an ophthalmic evaluation for ocular abnormalities which included intraocular pressure measurement with Goldmann applanation tonometry.Raised intraocular pressure was found in three patients (11%). Abnormality in cup-disc ratio was seen in only one patient with cup-disc ratio asymmetry of 0.4. All these four patients were taking only ziprasidone.Patients using ziprasidone were found to have abnormalities in both intraocular pressure and cup-disc ratio.