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Comparasion of granisetron and metoclopramide for prevention of nausea and vomiting following total cystectomy and ileal conduit

2007; National Library of Serbia; Volume: 54; Issue: 2 Linguagem: Inglês

10.2298/aci0702019l

2406-0887

Nebojša Ladjević, Ivana Likić-Ladjević, B. Krivic, J. Filimonovic, M. Acimovic, Dejan Dragičević, Rajka Argirović,

Sympathectomy and Hyperhidrosis Treatments

The objective of this study was to examine the use of granisetron in actual clinical practice and to compare effect of dose of 1 mg granisetron after total cystectomy plus ileal conduit with group of patients which received metoclopramide. Granisetron established total control of PONV in 93,33% patients. Granisetron is 40% more effective in PONV control than metoclopramide. Only minimal nausea episodes were observed in early postoperative period in patients who had received low dose of granisetron (1 mg i.v.). .