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Atherosclerosis of Radial and Internal Thoracic Arteries Used in Coronary Bypass: Atherosclerosis in Arterial Grafts

2007; Wiley; Volume: 22; Issue: 5 Linguagem: Inglês

10.1111/j.1540-8191.2007.00431.x

1540-8191

Síbel A. Özkan, Tankut Hakkı Akay, Bahadır Gültekin, Erdal Aslım, Ahmet Süha Arslan, B. Handan Özdemir, Necip Becit, Atılay Taşdelen,

Aortic Disease and Treatment Approaches

This study aimed to evaluate the degree and incidence of atherosclerosis in internal thoracic (ITA) and radial arteries (RA) harvested for coronary bypass grafting.The association of major clinical events and etiological factors for atherosclerosis was investigated in 770 arterial segments obtained prospectively from 480 patients. Potential risk factors for atherosclerosis were age, gender, smoking, diabetes mellitus, peripheral vascular disease, cerebrovascular disease, chronic renal failure, hypercholesterolemia, obesity, hypertension, and a positive family history.Six types of histological lesions have been defined; grade III or more was present in the RA in 47 (16%) patients and in the ITA in 30 (7%). The mean grade was 1.6 +/- 0.6 in the ITA and 2.1 +/- 0.9 in the RA (p < 0.001).RA had a significantly greater prevalence of atherosclerosis than the same patients' ITA. There was a strong correlation between ITA atherosclerosis and age. The presence of calcification may lead surgeons to avoid an extra incision according to risk factors, although most of these are not predictive.