Anthracyclinone syntheses using strong base induced cycloaddition of homophthalic anhydrides and related compounds
1984; Elsevier BV; Volume: 40; Issue: 22 Linguagem: Inglês
10.1016/s0040-4020(01)91513-3
ISSN1464-5416
AutoresYasumitsu Tamura, M. SASHO, Shuji Akai, Akimori Wada, Yasuyuki Kita,
Tópico(s)Synthesis of Organic Compounds
ResumoThe strong base induced cycloaddition of homophthalic anhydrides and related compounds to halo- 1,4-naphthoquinone derivatives has been shown to provide short convergent syntheses of anthracyclinones, 4-demethoxydaunomycinone (1), daunomycinone (2), 11-deoxydaunomycinone (3), and 11-deoxycarminomycinone (4).
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