Heart valvular disease in patients with Parkinson’s disease treated with high-dose pergolide
2003; Lippincott Williams & Wilkins; Volume: 61; Issue: 6 Linguagem: Inglês
10.1212/01.wnl.0000083985.00343.f2
ISSN1526-632X
AutoresGuy Van Camp, Anja Flamez, Bernard Cosyns, J. Goldstein, Celia Perdaens, D. Schoors,
Tópico(s)Adrenal and Paraganglionic Tumors
ResumoThe authors report the clinical, echocardiographic, and pathologic findings in two patients treated with more than 5 mg of pergolide daily who developed symptomatic severe heart failure due to restrictive valvular disease. They also describe the echocardiographic data of another eight patients taking similar doses of pergolide presenting no clinical signs of heart failure. The findings suggest a possible role of high doses of pergolide in inducing restrictive valvular disease.
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