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BIBTEX RIS

Guanosinetriphosphatase activity dependent on elongation factor Tu and ribosomal protein L7/L12.

1978; National Academy of Sciences; Volume: 75; Issue: 7 Linguagem: Inglês

10.1073/pnas.75.7.3192

ISSN

1091-6490

Autores

D. Donner, Richard Villems, Anders Liljas, C. G. Kurland,

Tópico(s)

Glycosylation and Glycoproteins Research

Resumo

Incubation of electrophoretically pure samples of the Escherichia coli 50S ribosomal protein L7/L12 together with elongation factor Tu leads to the hydrolysis of GTP. Addition of elongation factor Ts stimulates this reaction. Elongation factor G cannot replace elongation factor Tu for the ribosome-free GTPase reaction dependent on L7/L12. The data suggest that elongation factor Tu and the protein L7/L12 interact directly at the ribosomal A site.

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