Portal de Periódicos da CAPES

First experimental determination of two-bond 13C isotopic effects on 1H NMR chemical shifts

2008; Elsevier BV; Volume: 49; Issue: 16 Linguagem: Inglês

10.1016/j.tetlet.2008.02.097

1873-3581

Juan F. Espinosa, Teodor Parella,

Metabolomics and Mass Spectrometry Studies

For the first time, a simple NMR methodology is proposed for the accurate determination of the effect of the substitution of 12C by 13C on the chemical shifts of protons separated by two-bonds in small molecules in their natural abundance.