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Pulmonary Dead-Space Fraction as a Risk Factor for Death in the Acute Respiratory Distress Syndrome

2002; Massachusetts Medical Society; Volume: 346; Issue: 17 Linguagem: Inglês

10.1056/nejmoa012835

1533-4406

Thomas J. Nuckton, James A Alonso, Richard H Kallet, Brian M. Daniel, Jean‐François Pittet, Mark D. Eisner, Michael A. Matthay,

Cardiac Arrest and Resuscitation

No single pulmonary-specific variable, including the severity of hypoxemia, has been found to predict the risk of death independently when measured early in the course of the acute respiratory distress syndrome. Because an increase in the pulmonary dead-space fraction has been described in observational studies of the syndrome, we systematically measured the dead-space fraction early in the course of the illness and evaluated its potential association with the risk of death.