Artigo Acesso aberto Revisado por pares

Clinical and Biologic Activity of an Estrogenic Herbal Combination (PC-SPES) in Prostate Cancer

1998; Massachusetts Medical Society; Volume: 339; Issue: 12 Linguagem: Inglês

10.1056/nejm199809173391201

ISSN

1533-4406

Autores

Robert S. DiPaola, Huayan Zhang, George H. Lambert, Robert J. Meeker, Edward Licitra, Mohamed M. Rafi, Bao Ting Zhu, H. Spaulding, Susan Goodin, Michel B. Tolédano, William N. Hait, Michael A. Gallo,

Tópico(s)

Phytochemicals and Antioxidant Activities

Resumo

Herbal mixtures are popular alternatives to demonstrated therapies. PC-SPES, a commercially available combination of eight herbs, is used as a nonestrogenic treatment for cancer of the prostate. Since other herbal medicines have estrogenic effects in vitro, we tested the estrogenic activity of PC-SPES in yeast and mice and in men with prostate cancer.

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