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Amlodipine overdose causes prolonged calcium channel blocker toxicity

1998; Elsevier BV; Volume: 16; Issue: 5 Linguagem: Inglês

10.1016/s0735-6757(98)90011-0

1532-8171

Bruce D. Adams, William T. Browne,

Pharmacology and Obesity Treatment

Amlodipine is a relatively new agent that has the longest half-life of all calcium channel blockers. This report describes a severe overdose that resulted in prolonged and severe hemodynamic compromise for up to 10 days, but responded to aggressive therapy with calcium, glucagon, and other vasoactive medicines.