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BIBTEX RIS

Prevalence of a new auto-activating colony stimulating factor 3 receptor mutation (CSF3R-T595I) in acute myeloid leukemia and severe congenital neutropenia

2013; Ferrata Storti Foundation; Volume: 98; Issue: 5 Linguagem: Inglês

10.3324/haematol.2013.085050

ISSN

1592-8721

Autores

Renée Beekman, Marijke Valkhof, Paulette van Strien, Peter J.M. Valk, Ivo P. Touw,

Tópico(s)

Immune Response and Inflammation

Resumo

Colony-stimulating factor 3 (CSF3), also known as granulocyte-colony stimulating factor (G-CSF), is the main growth factor driving neutrophil production under physiological conditions and during episodes of microbial infections. A tight but dynamic balance between signal activation and attenuation

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