Portal de Periódicos da CAPES

Selectivity in bromination of aniline and N-substituted anilines encapsulated in β-cyclodextrin

1996; Elsevier BV; Volume: 52; Issue: 10 Linguagem: Inglês

10.1016/0040-4020(96)00027-0

1464-5416

Palaniyandi Velusamy, Kasi Pitchumani, C. Srinivasan,

Chemical Synthesis and Reactions

In contrast to the conventional bromination, aniline and N-methylaniline encapsulated in β-Cyclodextrin (β-CD) give ortho-bromoaniline and para-bromo-N-methylaniline respectively in larger yield. The results are explained on the basis of mode of complexation between β-CD and anilines. Aniline and N-methylaniline encapsulated in β-Cyclodextrin give ortho-bromoaniline and para-bromo-N-methylaniline respectively in larger yield.