Artigo Acesso aberto Revisado por pares

LYMPHOCYTE SUBSET DIFFERENCES FOLLOWING DEXAMETHASONE (DEX) THERAPY.† 1460

1996; Springer Nature; Volume: 39; Linguagem: Inglês

10.1203/00006450-199604001-01483

ISSN

1530-0447

Autores

Daniel B. Sobel, Kenneth A. Ault, Barbara A. Chilmonczyk,

Tópico(s)

Childhood Cancer Survivors' Quality of Life

Resumo

Premature infants frequently receive DEX for broncho-pulmonary dysplasia(BPD). Long term effects of this therapy on lymphocytes are unknown. Ten infants ([horizontal bar over]x 26 wks, 825 gm) who received DEX for BPD were compared with matched controls (CON). Blood was obtained prior to (PRE)([horizontal bar over]x d21), after (HIGH) ([horizontal bar over]x d26), at(END) of DEX ([horizontal bar over]x d58), and at term (TERM) ([horizontal bar over]x d97). Direct two-color immunofluorescent staining followed by flow cytometry was employed for cell surface marker determinations. Statistical significance was determined by T test.

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