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Demographic and blood genetic characteristics in an Amazonian population

1982; Elsevier BV; Volume: 11; Issue: 7 Linguagem: Inglês

10.1016/s0047-2484(82)80001-8

1095-8606

Lavínia Schüler‐Faccini, Francisco M. Salzano, M. Helena, Letícia Paiva Franco, Maria J. de Melo e Freitas, Moacyr Antônio Mestriner, Aguinaldo Luíz Simões,

Hemoglobinopathies and Related Disorders

Demographic, epidemiological and genetic studies are reported from 595 persons living in Parintins, a community situated at the extreme East of the State of Amazonas, Brazil. The average distance traveled by the adults studied from their birthplaces to Parintins was 116 kms. Marital distances, estimated in three generations, ranged from 35 km to 174 km, and parent-offspring distances from 88 km to 157 km. Most of these dispersion measures showed a high degree of correlation. The genetic data involved nine systems (ABO, Rh, Hb, ESD, CA2, Hp, Tf, Cp and Al). One special item of interest was the occurrence of the rare variant ESD4. Largely negative results concerning specific phenotype differences in malaria susceptibility, as well as in general mortality or fertility, were obtained. Preliminary quantitative estimates of the racial composition of this trihybrid mixed population indicates that it should be 67% White, 29% Indian and 4% Black.