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New Targets in Diarrhetic Shellfish Poisoning Control

2005; American Chemical Society; Volume: 68; Issue: 4 Linguagem: Inglês

10.1021/np040183t

1520-6025

Blanca Suárez‐Gómez, Marı́a L. Souto, Patricia G. Cruz, José J. Fernández, Manuel Norte,

Animal Ecology and Behavior Studies

The toxic profile of dinoflagellates varies even among identical species, raising an interesting question about the mechanism of toxin regulation and production. In consequence, it also poses a considerable problem in their control methods. In this paper, we report on the isolation and structural elucidation of several new ester derivatives of okadaic acid (OA) from artificial cultures of the genus Prorocentrum. These new compounds enlarge the range of target molecules that must be considered in the monitoring programs.