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Doubts concerning the recently reported human neutrophil lifespan of 5.4 days

2011; Elsevier BV; Volume: 117; Issue: 22 Linguagem: Inglês

10.1182/blood-2010-10-310532

1528-0020

Paul S. Tofts, Timothy Chevassut, Marica Cutajar, Nicholas G. Dowell, A. M. Peters,

Neonatal Respiratory Health Research

To the editor: Using orally administered deuterium-labeled water to label neutrophils in vivo, Pillay et al measured urinary and blood deuterium-to-proton enrichment ratios at intervals of ∼ 12 days over several weeks before and after termination of intake.[1][1] From mathematical modeling they