Ring closing metathesis of vinyl glycine derivatives
1998; Elsevier BV; Volume: 39; Issue: 34 Linguagem: Inglês
10.1016/s0040-4039(98)01270-2
ISSN1873-3581
AutoresJean‐Marc Campagne, Léon Ghosez,
Tópico(s)Chemical Synthesis and Analysis
ResumoRing closing metathesis of vinyl glycine derivatives using Grubbs' ruthenium catalyst has been performed successfully. The reaction works well with N-allyl amides derived from N-protected vinyl glycines. The use of a trityl protecting group allows the reaction to be performed successfully with the otherwise unreactive N-allyl vinyl glycine ester.
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