Metastatic Angiosarcoma of the Spleen After Accidental Radiation Exposure
1998; Lippincott Williams & Wilkins; Volume: 21; Issue: 2 Linguagem: Inglês
10.1097/00000421-199804000-00015
ISSN1537-453X
AutoresDavid Geffen, Howard J. Zirkin, Wilmosh Mermershtain, Yoram Cohen, Samuel Ariad,
Tópico(s)Sarcoma Diagnosis and Treatment
ResumoAngiosarcoma is a rare malignant tumor arising from endothelial cells of blood vessels or lymphatic channels. Therapeutic irradiation, thoriumdioxide administration, pyothorax, and polyvinyl chloride exposure have been shown to be predisposing factors for developing angiosarcoma. Accidental radiation exposure has not been associated with angiosarcoma. We present an unusual case of angiosarcoma of the spleen, with metastases to bone, liver, breast, and bone marrow, in a woman who lived near the Chernobyl nuclear facility in the former Soviet Union at the time of the reactor accident in 1986. To the best of our knowledge, this is the first report of metastatic angiosarcoma after accidental radiation exposure.
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