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EFFECT OF PROGESTINS ON GLUCOSE AND LIPID METABOLISM *

1977; Wiley; Volume: 286; Issue: 1 Linguagem: Inglês

10.1111/j.1749-6632.1977.tb29435.x

1749-6632

Paul A Beck,

Growth Hormone and Insulin-like Growth Factors

Annals of the New York Academy of SciencesVolume 286, Issue 1 p. 434-445 EFFECT OF PROGESTINS ON GLUCOSE AND LIPID METABOLISM* Paul Beck, Paul Beck Endocrinology Division Department of Medicine University of Colorado School of Medicine Denver, Colorado 80262Search for more papers by this author Paul Beck, Paul Beck Endocrinology Division Department of Medicine University of Colorado School of Medicine Denver, Colorado 80262Search for more papers by this author First published: March 1977 https://doi.org/10.1111/j.1749-6632.1977.tb29435.xCitations: 18 * Supported in part by United States Public Health Service Grants HD 02455 and FR 00051 and by a grant from Syntex Corporation. AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat References 1 Beck, P. 1969. Progestin enhancement of the plasma insulin response to glucose in rhesus monkeys. Diabetes 18: 146–152. 2 Neill, J. D., E. O. B. Johansson, J. K. Datta & E. Knobil. 1967. Relationship between the plasma levels of luteinizing hormone and progesterone during the normal menstrual cycle. J. Clin. Endocrinol. Metab. 27: 1167–1173. 3 Beck, P., R. L. Venable & D. L. Hoff. 1975. Mutual modification of glucose-stimulated serum insulin responses in female rhesus monkeys by ethinyl estradiol and nortestosterone derivatives. J. Clin. Endocrinol. Metab. 41: 44–53. 4 Kalkhoff, R. K., M. Jacobsen & D. Lemper. 1970. Progesterone, pregnancy and the augmented plasma insulin response. J. Clin. Endocrinol. Metab. 31: 24–28. 5 Costrini, N. V. & R. K. Kalkhoff. 1971. Relative effects of pregnancy, estradiol and progesterone on plasma insulin and pancreatic islet insulin secretion. J. Clin. Invest. 50: 992–999. 6 Kalkhoff, R. K., D. S. Schalch, J. L. Walker, P. Beck, D. M. Kipnis & W. H. Daughaday. 1964. Diabetogenic factors associated with pregnancy. Trans. Ass. Amer. Physicians 77: 270–278. 7 Matute, M. L. & R. K. Kalkhoff. 1973. Sex steroid influence on hepatic gluconeogenesis and glycogen metabolism. Endocrinology 92: 762–768. 8 Spellacy, W. N., W. C. Buhi & S. A. Birk. 1975. Effects of norethindrone on carbohydrate and lipid metabolism. Obstet. Gynecol. 46: 560–563. 9 Spellacy, W. N., W. C. Buhi & S. A. Birk. 1974. Norgestrel and carbohydrate-lipid metabolism: glucose, insulin and triglyceride changes during six months time of use. Contraception 9: 615–625. 10 Goldman, J. A. 1975. Effect of ethynodiol diacetate and combination-type oral contraceptive compounds on carbohydrate metabolism. I. Six month intravenous glucose tolerance study. Diabetologia 11: 45–48. 11 Beck, P. 1970. Comparison of the metabolic effects of chlormadinone acetate and conventional contraceptive steroids in man. J. Clin. Endocrinol. Metab. 30: 785–791. 12 Larsson-Cohn, U., B. Tengstrom & L. Wide. 1969. Glucose tolerance and insulin response during daily continuous low-dose oral contraceptive treatment. Acta Endocrinol. 62: 242–250. 13 Vermeulen, A., R. Daneels & M. Thiery. 1970. Effects of oral contraceptives on carbohydrate metabolism. Diabetologia 6: 519–523. 14 Adams, P. W. & V. Wynn. 1972. The effects of progestogen, megestrol acetate, on carbohydrate and lipid metabolism. J. Obstet. Gynaecol. Brit. Commonwealth 79: 744–752. 15 Spellacy, W. N., R. E. Newton, W. C. Buhi & S. A. Birk. 1973. Carbohydrate and lipid studies during six months' treatment with megestrol acetate. Amer. J. Obstet. Gynecol. 116: 1074–1078. 16 Beck, P., D. Zimmerman & R. P. Eaton. 1976. Effect of contraceptive steroids on arginine-stimulated glucagon and insulin secretion in women. III. Oral medroxy-progesterone acetate. Current Topics in Diabetes Research. Abstracts of the IXth Congress of the International Diabetes Foundation: 34. Excerpta Medica. Amsterdam , The Netherlands . 17 Spellacy, W. N., A. G. W. McLeod, W. C. Buhi, S. A. Birk & S. A. McCreary. 1970. Medroxyprogesterone acetate and carbohydrate metabolism: measurement of glucose, insulin, and growth hormone during six months time. Fertil. Steril. 21: 457–463. 18 Vermeulen, A. & M. Thiery. 1974. 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Invest. 11: 1756–1767. 25 Poledne, R. & P. A. Mayes. 1970. Lipolysis and the regulation of fatty acid metabolism in the liver. Biochem. J. 119: 47P–48P. 26 Havel, R. J. 1961. Conversion of plasma free fatty acids into triglycerides of plasma lipoprotein fractions in man. Metabolism 12: 1031–1034. 27 Fain, J. N., V. P. Kovacev & R. O. Scow. 1965. Effect of growth hormone and dexamethasone on lipolysis and metabolism in isolated fat cells of the rat. J. Biol. Chem. 240: 3522–3529. 28 Raben, M. S. & C. H. Hollenberg. 1959. Effect of growth hormone on plasma free fatty acids. J. Clin. Invest. 38: 484–488. 29 Heimberg, M., I. Weinstein & M. Kohout. 1969. The effects of glucagon, dibutyryl cyclic adenosine 3,5 monophosphate, and concentration of free fatty acid on hepatic lipid metabolism. J. Biol. Chem. 244: 5131–5139. 30 Spellacy, W. N., K. L. Carlson & S. L. Schade. 1967. Human growth hormone levels in normal subjects receiving an oral contraceptive. J. Amer. Med. Ass. 202: 451–454. 31 Davidson, M. B. & G. B. Holzman. 1973. Role of growth hormone in the alteration of carbohydrate metabolism induced by oral contraceptive agents. J. Clin. Endocrinol. Metab. 36: 246–255. 32 Spellacy, W. N., W. C. Buhi & S. A. Birk. 1972. The effect of estrogens on carbohydrate metabolism: glucose, insulin, and growth hormone studies on one hundred seventy-one women ingesting Premarin, mestranol, and ethinyl estradiol for six months. Amer. J. Obstet. Gynecol. 114: 378–390. 33 Spellacy, W. N., W. C. Buhi & S. A. Birk. 1971. Studies of ethynodiol diacetate and mestranol on blood glucose and plasma insulin. II. Twelve month oral glucose tolerance test. Contraception 3: 185–194. 34 Beck, P., R. P. Eaton, D. M. Arnet & R. N. Alsever. 1975. Effect of contraceptive steroids on arginine-stimulated glucagon and insulin secretion in women: I. Lipid physiology. Metabolism 24: 1055–1065. 35 Stokes, T. & V. Wynn. 1971. Serum-lipids in women on oral contraceptives. 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Steril. 24: 178–184. 41 Danowski, T. S., H. R. Wilson, R. C. Khurana, Y. Jung, A. R. Gonzalez & J. H. Sunder. 1973. Effects of a progestin, quingestanol, in older diabetic women. Hormone Res. 4: 84–96. 42 Glueck, C. J., S. Ford, Jr., P. Steiner, S. Buxton & R. Fallat. 1973. Amer. J. Obstet. Gynecol. 116: 689–693. 43 Glueck, C. J., R. I. Levy & D. S. Frederickson. 1971. Norethindrone acetate, postheparin lipolytic activity, and plasma triglycerides in familial types I, III, IV, and V hyperlipoproteinemia. Ann. Intern. Med. 75: 345–352. 44 Kissebah, A. H., P. Harrigan & V. Wynn. 1973. Mechanism of hypertriglyceridemia associated with contraceptive steroids. Hormone Metab. Res. 5: 184–190. 45 Glueck, C. J. 1971. Effects of oxandrolone on plasma triglycerides and post-heparin lipolytic activity in patients with types III, IV, and V familial hyperlipoproteinemia. Metabolism 20: 691–702. 46 Glueck, C. J., S. Ford, Jr., P. Steiner & R. Fallat. 1973. Triglyceride removal efficiency and lipoprotein lipases: effects of oxandrolone. Metabolism 22: 807–814. 47 Beck, P. & S. A. Wells. 1969. Comparison of the mechanisms underlying carbohydrate intolerance in subclinical diabetic women during pregnancy and during postpartum oral contraceptive treatment. J. Clin. Endocrinol. Metab. 29: 807–818. 48 Goldman, J. A., J. L. Ovadia & B. Eckerling. 1968. Effect of progesterone on glucose tolerance in women. Israel J. Med. Sci. 4: 878–882. 49 Spellacy, W. N., W. C. Buhi & S. A. Birk. 1972. The effect of the progestogen ethynodiol diacetate on glucose, insulin, and growth hormone after six months treatment. Acta Endocrinol. 70: 373–384. 50 Lewis, J. T., V. G. Foglia & R. R. Rodriguez. 1950. The effects of steroids on the incidence of diabetes in rats after subtotal pancreatectomy. Endocrinology 46: 111–121. 51 Houssay, B. A. 1951. Action of sex hormones on experimental diabetes. Brit. Med. J. 2: 505–510. 52 Kochakian, C. D. & G. Costa. 1959. The effect of testosterone propionate on the protein and carbohydrate metabolism in the depancreatized-castrated dog. Endocrinology 65: 298–309. 53 Sloan, J. M. & I. M. Oliver. 1975. Progestogen-induced diabetes in the dog. Diabetes 24: 337–344. 54 Beck, P. 1969. Effects of gonadal hormones and contraceptive steroids on glucose and insulin metabolism. In Metabolic Effects of Gonadal Hormones and Contraceptive Steroids. H. A. Salhanick, D. M. Kipnis & R. L. Vande Wiele, Eds.: 97–125. Plenum Publishing Corporation. New York , N.Y . 55 Gerich, J. E., M. Lorenzini, V. Schneider, J. H. Karam, J. Rivier, R. Guillemin & P. H. Forsham. 1974. Effects of somatostatin on plasma glucose and glucagon levels in human diabetes mellitus. N. Engl. J. Med. 291: 544–547. 56 Srivastava, M. C., N. W. Oakley, C. V. Tompkins, P. H. Sönksen & V. Wynn. 1975. Insulin metabolism, insulin sensitivity and hormonal responses to insulin infusion in patients taking oral contraceptive steroids. Eur. J. Clin. Invest. 5: 425–433. 57 Lei, K. Y., M. G. Yang, D. Oberleas & A. S. Prasad. 1975. Oral contraceptives: effect on plasma insulin response to glucose and on the response to insulin and 2-deoxyglucose uptake by peripheral tissue. Proc. Soc. Exp. Biol. Med. 149: 417–421. Citing Literature Volume286, Issue1Biochemical Actions of Progesterone and ProgestinsMarch 1977Pages 434-445 ReferencesRelatedInformation