A Facile One-Step in situ Functionalization of Quantum Dots with Preserved Photoluminescence for Bioconjugation
2007; American Chemical Society; Volume: 129; Issue: 20 Linguagem: Inglês
10.1021/ja071434y
ISSN1943-2984
AutoresQiangbin Wang, Yang Xu, Xiao-Hang Zhao, Yung Chang, Yan Liu, Lijing Jiang, Jaswinder Sharma, Dong‐Kyun Seo, Hao Yan,
Tópico(s)Nanocluster Synthesis and Applications
ResumoHerein we report a new and simple method of in situ functionalization of CdSe QDs and surface passivation by a thin ZnS shell at the same time. This method avoids a second-step ligand exchange after the core−shell formation and preserved high quantum yield of the QDs. We demonstrated that such prepared QDs can serve as excellent nanomaterial for bioconjugation. Different antibodies were conjugated to the MPA-functionalized QDs and resulted in highly stable and highly photoluminescent nanoparticles for cell labeling purposes.
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