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Artigo Revisado por pares
BIBTEX RIS

Mechanisms of resistance to aminoglycosides

1977; Elsevier BV; Volume: 62; Issue: 6 Linguagem: Inglês

10.1016/0002-9343(77)90654-4

ISSN

1555-7162

Autores

Julian Davies, Patrice Courvalin,

Tópico(s)

Essential Oils and Antimicrobial Activity

Resumo

Bacterial resistance to aminoglycoside antibiotics occurs by a variety of mechanisms. In clinical situations the most common mechanism is plasmid-determined modification of the drug that leads to a block of transport of the antibiotic into the cell. Amikacin, a semisynthetic aminoglycoside, is effective against a number of resistant strains because it has fewer sites of modification.

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