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Spontaneous Liver Hemorrhage During Laparotomy for Necrotizing Enterocolitis: A Potential Role for Recombinant Factor VIIa

2005; Elsevier BV; Volume: 147; Issue: 6 Linguagem: Inglês

10.1016/j.jpeds.2005.07.034

1097-6833

Peter M. Filan, John F. Mills, Tom Clarnette, H. Ekert, Paul G. Ekert,

Esophageal and GI Pathology

Necrotizing enterocolitis remains a serious condition in very low birth weight infants, particularly in those infants who require surgery. Perioperative hemorrhage is a potentially fatal complication in this population. We describe our experience in 4 premature infants with necrotizing enterocolitis who received recombinant factor VIIa to manage life-threatening intraoperative hemorrhage.