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Long‐Term Outcome of Deceased Donor Renal Transplants Correlates with the 30‐Day Creatinine Reduction Ratio

2005; Elsevier BV; Volume: 5; Issue: 9 Linguagem: Inglês

10.1111/j.1600-6143.2005.01011.x

1600-6143

Roberto S. Kalil, Christopher S. Dyer, Stephen C. Rayhill,

Organ Transplantation Techniques and Outcomes

A simplified model to correlate early allograft function with long-term allograft survival in recipients of deceased donor renal transplants (DDRT) remains challenging. We propose here a novel approach, using the change from the pretransplant creatinine to the 30-day posttransplant creatinine. The outcomes of 153 consecutive DDRT performed at our center between January 1998 and March 2001 were reviewed. The percentage change in creatinine from the pretransplant to 1 month posttransplant, termed here, the creatinine reduction ratio (CRR), was calculated as follows: (pretransplant creatinine-creatinine at 1 month)/pretransplant creatinine *100%. Patients were divided as follows: group 1 CRR>or=67% and group 2 or=67% with determinants of long-term outcome, the risk ratio of graft loss during the observational period was 0.26 (p=0.001). The creatinine reduction ratio, when stratified by a level of >or=67% has a strong correlation with superior long-term allograft survival in recipients of DDRT.