Porous Collagen Sponge Wound Dressings: in vivo and in vitro Studies
1987; SAGE Publishing; Volume: 2; Issue: 4 Linguagem: Inglês
10.1177/088532828700200404
ISSN1530-8022
Autores Tópico(s)Electrospun Nanofibers in Biomedical Applications
ResumoCollagen-based materials can be formed into a three-dimensional sponge for use as a wound dressing and as a support for cell cultured skin components. Factors such as biocompatibility, morphological structure and addition of non-collagenous molecules to collagen are analyzed and discussed. Large pores or channels, interchannel communications and combinations of macromolecules of the connective tissue enhance wound tissue infiltration in vivo as well as cell growth in vitro into collagen sponges. The presence of such factors can be useful in patients with excised burn wounds and pressure skin ulcers.
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