SIZE REDUCTION OF A PROLACTIN SECRETING ADENOMA DURING LONG-TERM TREATMENT WITH THE DOPAMINE AGONIST LISURIDE
1980; Wiley; Volume: 12; Issue: 1 Linguagem: Inglês
10.1111/j.1365-2265.1980.tb03131.x
ISSN1365-2265
AutoresP. G. Chiodini, Antonio Liuzzi, G. Verde, Renato Cozzi, F Silvestrini, M Marsili, R. Horowski, F Passerini, G. Luccarelli, P. G. BORGHI,
Tópico(s)Pituitary Gland Disorders and Treatments
ResumoSUMMARY A 38–year‐old amenorrhoeic woman suffering from a prolactin (PRL) secreting adenoma, which had suprasellar extension as shown by carotid angiography and computed axial tomography (CAT), was treated with a dopamine agonist (lisuride). PRL levels were lowered and after 1 year of treatment CAT showed a marked reduction of the tumour size. After 2 years of treatment menstruation returned and CAT demonstrated a further reduction of the adenomatous tissue. This study supports the suggestion that dopamine agonists possess an anti‐pro‐liferative effect on tumoural lactotrophic cells of humans.
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