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BIBTEX RIS

Antimicrobial and antileishmanial activity of essential oil from the leaves of Annona foetida (Annonaceae)

2009; Brazilian Chemical Society; Volume: 32; Issue: 1 Linguagem: Inglês

10.1590/s0100-40422009000100015

ISSN

1678-7064

Autores

Emmanoel Vilaça Costa, Maria Lúcia B. Pinheiro, Jefferson Rocha de Andrade Silva, Beatriz Helena Lameiro de Noronha Sales Maia, Marta Cristina Teixeira Duarte, Ana Cláudia F. Amaral, Gérzia Maria de Carvalho Machado, Leonor L. Leon,

Tópico(s)

Traditional and Medicinal Uses of Annonaceae

Resumo

bicyclogermacrene (35.12%), (E)-caryophyllene (14.19%) and α-copaene (8.19%). The antimicrobial and antileishmanial activities were investigated. The oil showed potent antimicrobial activity against Candida albicans and Rhodococcus equi. The oil also showed significant antileishmanial activity, giving the best results against Leishmania guyanensis. A preliminary cytotoxicity assay for this oil was carried out on hamster and mice (Balb/c) peritoneal macrophages. The results obtained were similar to pentamidine and considered not to be cytotoxic to macrophages.

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